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Lung cancer clinical trials in Los Angeles

Clinical trials are research studies that test new ways to treat, find or manage lung cancer. Some compare a new medicine or combination with today’s standard treatment. Others study radiation, surgery, screening or ways to ease side effects.

Each study has its own rules about who can join. For lung cancer these often include the type (non-small cell or small cell), the stage, results of tumor or blood (biomarker) tests such as EGFR, ALK, KRAS or PD-L1, and past treatments.

The list below shows lung cancer studies on ClinicalTrials.gov, the public U.S. registry, that list at least one recruiting site within about 50 miles of downtown Los Angeles.

Answer 4 quick questions →No records needed. See how many recruiting studies may fit. Call Aria (855) 606-1679CureGate’s assistant, in English or Spanish.

Clinical trials are research and are not guaranteed to help. CureGate does not provide medical advice.

239 recruiting lung cancer studies near Los Angeles

Data from ClinicalTrials.gov as of November 3, 2026. Study status can change at any time. Titles are shown as registered. Confirm details with each study team.

  1. Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

    Phase
    3
    Recruiting in
    Anaheim, Baldwin Park, Bellflower, Fontana, Harbor City, Irvine, Long Beach, Los Angeles, Ontario, Panorama City, Riverside, Woodland Hills
    Last updated

  2. A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Orange
    Last updated

  3. Safety and Efficacy of OBX-115 in Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  4. Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

    Phase
    3
    Recruiting in
    Burbank
    Last updated

  5. Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

    Phase
    3
    Recruiting in
    Beverly Hills, Los Angeles, Torrance
    Last updated

  6. A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

    Phase
    2
    Recruiting in
    Lancaster, Long Beach, South Pasadena, Upland
    Last updated

  7. Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Fountain Valley, Irvine
    Last updated

  8. A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  9. A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

    Phase
    2/3
    Recruiting in
    Glendale, Orange
    Last updated

  10. A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  11. A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation

    Phase
    3
    Recruiting in
    Glendale, Los Angeles
    Last updated

  12. A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

    Phase
    2
    Recruiting in
    Duarte, Irvine
    Last updated

  13. A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  14. Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint Inhibitor Therapy

    Phase
    3
    Recruiting in
    El Segundo, Fountain Valley, Fullerton, Irvine, Newport Beach
    Last updated

  15. Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

    Phase
    3
    Recruiting in
    Fullerton, Los Angeles, Orange
    Last updated

  16. Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

    Phase
    3
    Recruiting in
    Glendale, Orange, Santa Monica
    Last updated

  17. A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Fountain Valley, Los Alamitos, Torrance
    Last updated

  18. Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

    Phase
    3
    Recruiting in
    Beverly Hills, Los Angeles, Tarzana, Torrance
    Last updated

  19. Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

    Phase
    3
    Recruiting in
    Duarte, Newport Beach
    Last updated

  20. Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

    Phase
    2/3
    Recruiting in
    Anaheim, Cerritos, Long Beach, Los Alamitos
    Last updated

  21. First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

    Phase
    1/2
    Recruiting in
    Duarte, Huntington Beach, Irvine
    Last updated

  22. SW-682 in Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles, Santa Monica
    Last updated

  23. Study of XB010 in Subjects With Solid Tumors

    Phase
    1
    Recruiting in
    Irvine, Los Angeles
    Last updated

  24. A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  25. A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

    Phase
    3
    Recruiting in
    Fullerton, Long Beach, Los Angeles
    Last updated

  26. Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

    Phase
    1
    Recruiting in
    Glendale, Long Beach, Los Angeles
    Last updated

  27. A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

    Phase
    3
    Recruiting in
    Duarte, Huntington Beach, Irvine, Lancaster
    Last updated

  28. Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

    Phase
    1/2
    Recruiting in
    Beverly Hills, Fullerton, Los Angeles, Newport Beach, Santa Monica
    Last updated

  29. Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

    Phase
    1/2
    Recruiting in
    Duarte, Irvine
    Last updated

  30. Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

    Phase
    3
    Recruiting in
    Burbank
    Last updated

  31. A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

    Phase
    3
    Recruiting in
    Anaheim, Beverly Hills, Los Alamitos
    Last updated

  32. DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  33. A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  34. Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

    Phase
    1
    Recruiting in
    Duarte, Los Angeles, Orange
    Last updated

  35. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    Phase
    not listed
    Recruiting in
    Burbank, Long Beach
    Last updated

  36. Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma

    Phase
    2
    Recruiting in
    Duarte
    Last updated

  37. A Study of MGC026 in Participants With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  38. Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

    Phase
    3
    Recruiting in
    Anaheim, Beverly Hills, Fountain Valley
    Last updated

  39. A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

    Phase
    3
    Recruiting in
    Anaheim, Beverly Hills
    Last updated

  40. A Study to Investigate ALE.P02 as a Monotherapy or in Combination With Pembrolizumab in Adult Patients With Selected CLDN1+ Solid Tumors

    Phase
    1/2
    Recruiting in
    Fullerton, Los Angeles
    Last updated

  41. A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

    Phase
    1/2
    Recruiting in
    Duarte, Irvine
    Last updated

  42. An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

    Phase
    4
    Recruiting in
    Glendale, Lakewood, Long Beach
    Last updated

  43. Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Glendale
    Last updated

  44. Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

    Phase
    1/2
    Recruiting in
    Fullerton, Santa Monica
    Last updated

  45. A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

    Phase
    3
    Recruiting in
    Fullerton, Long Beach
    Last updated

  46. Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

    Phase
    2
    Recruiting in
    Orange
    Last updated

  47. Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

    Phase
    not listed
    Recruiting in
    Santa Monica
    Last updated

  48. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

    Phase
    2
    Recruiting in
    Duarte
    Last updated

  49. A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

    Phase
    3
    Recruiting in
    Beverly Hills
    Last updated

  50. Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  51. Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

    Phase
    Not applicable
    Recruiting in
    Long Beach, West Los Angeles
    Last updated

  52. A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

    Phase
    3
    Recruiting in
    Santa Monica
    Last updated

  53. Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Fountain Valley, Los Angeles
    Last updated

  54. A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  55. A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

    Phase
    2/3
    Recruiting in
    Los Angeles
    Last updated

  56. A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

    Phase
    1
    Recruiting in
    Fullerton, Orange
    Last updated

  57. A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

    Phase
    3
    Recruiting in
    Beverly Hills, Fountain Valley, Los Alamitos, Los Angeles
    Last updated

  58. A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  59. A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  60. A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  61. A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  62. A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

    Phase
    2
    Recruiting in
    Irvine
    Last updated

  63. A 2-part Phase 1/2 Open-label Trial on ODM-212

    Phase
    1/2
    Recruiting in
    Los Angeles, Orange
    Last updated

  64. Study of PF-07248144 in Advanced or Metastatic Solid Tumors

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  65. Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  66. A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles, Santa Monica
    Last updated

  67. Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

    Phase
    1/2
    Recruiting in
    Irvine, Los Angeles
    Last updated

  68. Intratumoral N17350 in Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  69. AOH1996 for the Treatment of Refractory Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Long Beach
    Last updated

  70. Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  71. Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Anaheim
    Last updated

  72. A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

    Phase
    3
    Recruiting in
    Los Angeles
    Last updated

  73. A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

    Phase
    3
    Recruiting in
    Los Angeles
    Last updated

  74. Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

    Phase
    2
    Recruiting in
    Beverly Hills, Los Angeles, Torrance
    Last updated

  75. Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  76. A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  77. AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  78. Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

    Phase
    2
    Recruiting in
    Corona, Duarte, Huntington Beach, Irvine, Lancaster, Long Beach, Newport Beach, South Pasadena, Torrance, Upland
    Last updated

  79. Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease

    Phase
    Not applicable
    Recruiting in
    Duarte
    Last updated

  80. A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

    Phase
    3
    Recruiting in
    Beverly Hills, Los Angeles, Newport Beach, Orange
    Last updated

  81. A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

    Phase
    3
    Recruiting in
    Santa Monica
    Last updated

  82. SMP-3124LP in Adults With Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  83. A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

    Phase
    2
    Recruiting in
    Santa Monica
    Last updated

  84. A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  85. BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

    Phase
    3
    Recruiting in
    Glendale, Long Beach, Los Angeles
    Last updated

  86. KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  87. A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  88. A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

    Phase
    2
    Recruiting in
    Los Angeles, Orange
    Last updated

  89. A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

    Phase
    1/2
    Recruiting in
    Santa Monica
    Last updated

  90. Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

    Phase
    3
    Recruiting in
    Newport Beach
    Last updated

  91. Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  92. Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  93. A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Irvine
    Last updated

  94. A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

    Phase
    3
    Recruiting in
    Fullerton
    Last updated

  95. Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

    Phase
    3
    Recruiting in
    Duarte, Irvine, Los Angeles
    Last updated

  96. Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

    Phase
    2
    Recruiting in
    Beverly Hills, Los Angeles, Tarzana, Torrance
    Last updated

  97. Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

    Phase
    2/3
    Recruiting in
    Anaheim, Baldwin Park, Bellflower, Beverly Hills, Duarte, Fontana, Harbor City, Irvine, Lancaster, Los Angeles, Ontario, Panorama City, Riverside, Tarzana, Torrance, Upland, Woodland Hills
    Last updated

  98. Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

    Phase
    2/3
    Recruiting in
    Irvine, Orange
    Last updated

  99. Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Duarte, Irvine
    Last updated

  100. Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  101. Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Anaheim, Fountain Valley, Glendale, Laguna Hills, Long Beach, Los Alamitos, Los Angeles, Riverside, Torrance, Van Nuys
    Last updated

  102. Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

    Phase
    1/2
    Recruiting in
    Fullerton, Los Angeles, Panorama City
    Last updated

  103. Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  104. A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Los Angeles
    Last updated

  105. Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Los Angeles, Orange
    Last updated

  106. Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  107. A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

    Phase
    2
    Recruiting in
    Duarte
    Last updated

  108. LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

    Phase
    3
    Recruiting in
    Fullerton, Newport Beach
    Last updated

  109. A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Irvine, Los Angeles, Newport Beach, Orange
    Last updated

  110. Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

    Phase
    1/2
    Recruiting in
    Duarte, Irvine
    Last updated

  111. A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

    Phase
    2/3
    Recruiting in
    Duarte, Irvine, Los Angeles, Newport Beach, Santa Monica, Upland
    Last updated

  112. A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

    Phase
    2/3
    Recruiting in
    Duarte, Irvine
    Last updated

  113. A Study of ZW251 in Participants With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  114. The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  115. Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

    Phase
    3
    Recruiting in
    Beverly Hills
    Last updated

  116. A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

    Phase
    1/2
    Recruiting in
    Newport Beach
    Last updated

  117. Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  118. Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

    Phase
    3
    Recruiting in
    Newport Beach, Orange
    Last updated

  119. A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  120. A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

    Phase
    1
    Recruiting in
    Duarte, Los Angeles, Newport Beach, Santa Monica
    Last updated

  121. Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

    Phase
    3
    Recruiting in
    Long Beach
    Last updated

  122. A Study of PHN-012 in Patients With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  123. A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  124. Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles, Newport Beach
    Last updated

  125. This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

    Phase
    3
    Recruiting in
    Fullerton
    Last updated

  126. A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  127. Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

    Phase
    1/2
    Recruiting in
    Beverly Hills, Glendale, Los Angeles
    Last updated

  128. Pan-tumor MRD Study

    Phase
    not listed
    Recruiting in
    Glendale
    Last updated

  129. A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  130. A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Duarte, Irvine
    Last updated

  131. A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  132. Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

    Phase
    1/2
    Recruiting in
    Orange
    Last updated

  133. A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

    Phase
    1
    Recruiting in
    Duarte, Irvine, Los Angeles, Orange, Santa Monica
    Last updated

  134. Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

    Phase
    not listed
    Recruiting in
    Torrance
    Last updated

  135. Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

    Phase
    not listed
    Recruiting in
    Los Angeles
    Last updated

  136. A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  137. Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

    Phase
    1
    Recruiting in
    Beverly Hills, Duarte, Orange, Santa Monica
    Last updated

  138. Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)

    Phase
    Not applicable
    Recruiting in
    Anaheim, Costa Mesa, Irvine, Laguna Hills, Newport Beach, Orange, Santa Ana, Tustin, Yorba Linda
    Last updated

  139. Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

    Phase
    3
    Recruiting in
    Anaheim, Beverly Hills, Cerritos, Los Angeles, Orange, Torrance
    Last updated

  140. A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Irvine
    Last updated

  141. A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  142. Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  143. A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

    Phase
    1/2
    Recruiting in
    Duarte
    Last updated

  144. Statins to Prevent Cancer Associated Blood Clots

    Phase
    4
    Recruiting in
    Irvine
    Last updated

  145. TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  146. A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  147. ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

    Phase
    not listed
    Recruiting in
    Newport Beach
    Last updated

  148. A Phase 1/1b Study of IAM1363 in HER2 Cancers

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  149. A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  150. Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  151. A Study of IDP-001 in Advanced or Metastatic Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  152. A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  153. FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  154. Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

    Phase
    2
    Recruiting in
    Duarte, Irvine
    Last updated

  155. Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  156. Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Los Alamitos, Los Angeles, Orange, Santa Monica
    Last updated

  157. A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

    Phase
    1/2
    Recruiting in
    Beverly Hills, Los Angeles, Santa Monica
    Last updated

  158. Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

    Phase
    3
    Recruiting in
    Anaheim, Bellflower, Downey, Fontana, Long Beach, Los Angeles, Orange
    Last updated

  159. Patient-Derived Xenografts to Reduce Cancer Health Disparities

    Phase
    not listed
    Recruiting in
    Orange
    Last updated

  160. Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  161. A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

    Phase
    1
    Recruiting in
    Duarte, Irvine
    Last updated

  162. A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles, Newport Beach
    Last updated

  163. A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Long Beach
    Last updated

  164. Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  165. Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

    Phase
    1
    Recruiting in
    Beverly Hills, Los Angeles, Torrance
    Last updated

  166. A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

    Phase
    3
    Recruiting in
    Fullerton, Los Angeles
    Last updated

  167. A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

    Phase
    1/2
    Recruiting in
    Irvine
    Last updated

  168. Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  169. Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  170. AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  171. Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

    Phase
    1/2
    Recruiting in
    Duarte, Glendale, Los Angeles
    Last updated

  172. Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  173. DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  174. A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Irvine, Orange
    Last updated

  175. A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  176. A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

    Phase
    1
    Recruiting in
    Santa Monica
    Last updated

  177. A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  178. Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

    Phase
    1/2
    Recruiting in
    Orange
    Last updated

  179. A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

    Phase
    1/2
    Recruiting in
    Duarte, Los Angeles
    Last updated

  180. Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

    Phase
    2
    Recruiting in
    Orange
    Last updated

  181. Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

    Phase
    3
    Recruiting in
    Duarte, Irvine
    Last updated

  182. Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer

    Phase
    Not applicable
    Recruiting in
    Los Angeles
    Last updated

  183. ILKN421H Plus Pembrolizumab in Advanced Non-Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  184. Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

    Phase
    Not applicable
    Recruiting in
    Duarte
    Last updated

  185. A Study of Sigvotatug Vedotin in Advanced Solid Tumors

    Phase
    1
    Recruiting in
    Anaheim, Fullerton, Los Angeles, Santa Monica
    Last updated

  186. A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  187. EXoPERT EMERALD Clinical Study

    Phase
    not listed
    Recruiting in
    Long Beach, Los Angeles
    Last updated

  188. Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  189. Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  190. Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

    Phase
    not listed
    Recruiting in
    Duarte
    Last updated

  191. A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  192. Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

    Phase
    1
    Recruiting in
    Duarte, Irvine, Los Angeles
    Last updated

  193. A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  194. First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Orange
    Last updated

  195. A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  196. A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

    Phase
    1
    Recruiting in
    Beverly Hills, Santa Monica
    Last updated

  197. Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  198. Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

    Phase
    2
    Recruiting in
    Beverly Hills, Los Angeles, Torrance
    Last updated

  199. BBO-11818 in Adult Subjects With KRAS Mutant Cancer

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  200. Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

    Phase
    3
    Recruiting in
    Los Angeles, Orange
    Last updated

  201. Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

    Phase
    2/3
    Recruiting in
    Anaheim, Baldwin Park, Bellflower, Beverly Hills, Burbank, Duarte, Fontana, Harbor City, Irvine, Lancaster, Long Beach, Los Angeles, Ontario, Panorama City, Riverside, South Pasadena, Torrance, Upland, Woodland Hills
    Last updated

  202. Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

    Phase
    1/2
    Recruiting in
    Orange, Santa Monica
    Last updated

  203. A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

    Phase
    2
    Recruiting in
    Beverly Hills, Fountain Valley
    Last updated

  204. Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

    Phase
    Not applicable
    Recruiting in
    Duarte, Fullerton, Los Angeles
    Last updated

  205. A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers

    Phase
    2/3
    Recruiting in
    Duarte
    Last updated

  206. Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  207. TATE and Pembrolizumab (MK3475) in mCRC and NSCLC

    Phase
    2
    Recruiting in
    Orange
    Last updated

  208. Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

    Phase
    1
    Recruiting in
    Orange
    Last updated

  209. A Study of VET3-TGI in Patients With Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles, Orange
    Last updated

  210. A Study of DB-1310 in Advanced/Metastatic Solid Tumors

    Phase
    1/2
    Recruiting in
    Santa Monica
    Last updated

  211. Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

    Phase
    1
    Recruiting in
    Duarte, Irvine
    Last updated

  212. A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Los Angeles, Newport Beach, Santa Monica
    Last updated

  213. Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

    Phase
    1
    Recruiting in
    Duarte, Los Angeles
    Last updated

  214. Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study

    Phase
    not listed
    Recruiting in
    Los Angeles
    Last updated

  215. Phase II Trial of Lung Chemoemobolization

    Phase
    2
    Recruiting in
    Duarte
    Last updated

  216. Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

    Phase
    Not applicable
    Recruiting in
    Duarte, Irvine, Upland
    Last updated

  217. Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

    Phase
    2
    Recruiting in
    Orange
    Last updated

  218. Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma

    Phase
    Early Phase 1
    Recruiting in
    Los Angeles
    Last updated

  219. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  220. GEMINI-NSCLC: NSCLC Biomarker Study

    Phase
    not listed
    Recruiting in
    Fountain Valley, Los Angeles
    Last updated

  221. Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects

    Phase
    not listed
    Recruiting in
    Orange
    Last updated

  222. cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

    Phase
    not listed
    Recruiting in
    Duarte
    Last updated

  223. A Study of MT-4561 in Patients With Various Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  224. Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

    Phase
    2
    Recruiting in
    Duarte, Irvine
    Last updated

  225. An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  226. Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

    Phase
    Not applicable
    Recruiting in
    Los Angeles
    Last updated

  227. Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

    Phase
    Not applicable
    Recruiting in
    Long Beach
    Last updated

  228. A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

    Phase
    1/2
    Recruiting in
    Los Angeles, Newport Beach
    Last updated

  229. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    Phase
    not listed
    Recruiting in
    Duarte, Irvine, Orange
    Last updated

  230. A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

    Phase
    1/2
    Recruiting in
    Beverly Hills
    Last updated

  231. A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  232. A Study of NX-1607 in Adults With Advanced Malignancies

    Phase
    1
    Recruiting in
    Los Angeles
    Last updated

  233. A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

  234. Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

    Phase
    not listed
    Recruiting in
    Los Angeles
    Last updated

  235. Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

    Phase
    Not applicable
    Recruiting in
    Orange
    Last updated

  236. APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

    Phase
    2
    Recruiting in
    Los Angeles
    Last updated

  237. Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

    Phase
    1
    Recruiting in
    Duarte
    Last updated

  238. Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

    Phase
    1
    Recruiting in
    Beverly Hills
    Last updated

  239. A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

    Phase
    1/2
    Recruiting in
    Los Angeles
    Last updated

Not sure where to start?

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Frequently asked questions

Do I need biomarker test results first?

Not to start looking, but many lung cancer studies require specific tumor changes, such as EGFR, ALK, KRAS or PD-L1. If you have tumor or blood (liquid biopsy) test results, keep them handy. If you are not sure whether testing was done, ask your oncologist.

What is a clinical trial?

A clinical trial is a research study with people. It tests whether a new medicine, combination, procedure or approach is safe and how well it works compared with what is used today. Taking part is always voluntary, and you can leave a study at any time.

How do I know if a study fits?

Every study lists who can join (eligibility criteria), such as the exact type and stage of cancer, test results, past treatments and overall health. Only the study team can confirm eligibility. Your oncologist can help you decide whether a study is worth a closer look.

Does it cost anything to take part in a study?

It depends on the study. Some costs may be covered by the study and others billed to insurance. Ask the study team what is covered before you decide. CureGate’s matching service itself is free for patients and families.

Is CureGate running these studies?

No. CureGate is an independent matching service. The studies listed here are run by their sponsors and research sites, and a listing on this page is not a recommendation of any study.

How often is this list updated?

The list comes from ClinicalTrials.gov and shows the date it was pulled. A study’s status can change at any time, so always confirm details with the study team.

How can CureGate help?

CureGate’s service is free. Answer four quick questions (no records needed) to see how many recruiting studies may fit, call Aria at (855) 606-1679, or ask a CureGate research specialist to call you back. Nothing is shared with a study site unless you say so.

Can I search for a family member?

Yes. Many people use CureGate for a parent, spouse or friend, with that person’s permission.

Clinical trials are research and are not guaranteed to help. CureGate does not provide medical advice.